It's an up-and-down day for favorites and the husband-and-wife duo of Gaël Monfils and Elina Svitolina wo their singles matches.

Iga Swiatek, a self-described “control freak,” is taking new precautions — including holding on to extra samples of medicine she takes, in case they need to be tested at some point — after a doping case she describes as probably the worst time in her life.

While Sinner will take on Rune, the other matches will see Italy's L. Sonego take on L. Tien who managed to get past Medvedev on his way here.